گنادورولین
Type of medicine
Target species
Download product catalog
Packaging
10 mL vial
Compounds
Gonadorelin acetate
Mechanism of the Effect
This drug is transported to the pituitary gland through the portal venous circulation and stimulates the anterior part of the gland to increase the secretion of gonadotropins — follicle-stimulating hormone (FSH) and luteinizing hormone (LH) — which promote follicle development and corpus luteum formation in females, and spermatogenesis in males. The onset of action is approximately 2 hours, and its half-life is less than 3 hours. During this time, the peptide is broken down into amino acids and eliminated from the tissues.
Use case
Cow (female):
Induction of ovulation
Fixed-time artificial insemination programs
Treatment of ovarian cysts
Synchronization of ovulation
Delayed ovulation
Increased fertility rate following artificial insemination and embryo transfer
Mare:
Cystic ovarian changes with or without signs of estrus
Absence of estrus in non-cyclic mares
Induction of ovulation
Greater assurance of ovulation and mating by stallion
Increased fertility in prolonged or irregular estrus
Sheep:
Synchronization of ovulation
Stimulation of sexual function
The amount and how to use
This drug is administered intramuscularly.
Cattle: 2.5 mL (a 5 mL dose is recommended only for the treatment of ovarian cysts)
Mare: 5 mL
Sheep: 2.5 mL
Caution
Use only in healthy animals free of infection.
Use with caution during pregnancy and lactation, and only under veterinary supervision.
Avoid injecting into infected or inflamed areas.
In case of a hypersensitivity reaction, discontinue use and monitor the animal closely.
Store the product at 2–8°C and protect from freezing.
Concurrent use with other medications should be done only after consulting a veterinarian.
Drug interference
Concurrent use with other hormonal drugs (such as progesterone or estrogens) may alter the effects of gonadorelin.
Non-steroidal anti-inflammatory drugs (NSAIDs) can reduce the hormonal response to gonadorelin.
Simultaneous use with immunosuppressive agents may weaken the therapeutic response.
Always consult a veterinarian before co-administering medications to avoid potential interactions.
Maintenance conditions
Store in a dark place at a temperature between 8–15°C. Protect from freezing.
