Packaging
500-gram and 1-kilogram sachets
Compounds
Each gram of Neomycin 20% Rooyan powder contains 200 mg of neomycin (sulfate).
Mechanism of the Effect
Neomycin belongs to the aminoglycoside group and exerts its antibacterial effect by binding to the 30S subunit of bacterial ribosomes, disrupting the translation and synthesis of vital bacterial proteins.
This action results in bacterial death (bactericidal effect). Neomycin is primarily effective against Gram-negative and some Gram-positive bacteria.
Use case
Neomycin 20% has limited intestinal absorption, making it more effective against Gram-negative bacteria in the gastrointestinal tract.
Neomycin sulfate primarily acts against aerobic Gram-negative bacteria such as Escherichia coli, Klebsiella, Proteus, Salmonella, and some Gram-positive bacteria; however, it is not significantly effective against anaerobic bacteria.
This medication is prescribed for the treatment of bacterial gastrointestinal infections such as various types of enteritis and diarrhea in livestock and poultry.
The amount and how to use
Poultry:
Drinking water: Dissolve one 500-gram sachet in 500 liters of drinking water for 3 to 5 consecutive days
Calves, lambs, and kids:
Administer 12–14 mg of neomycin (sulfate) per kg of live body weight daily for 3 to 5 consecutive days
Caution
Neomycin sulfate should not be used for more than 5 consecutive days.
This medication should not be used in cases of renal failure, intestinal obstruction, or known hypersensitivity to the drug.
Drug interference
Concurrent administration with aminoglycosides and diuretics such as furosemide is not recommended.
Maintenance conditions
Store in a dry place, below 30°C, and away from light.
