Packaging
Available in 100 ml and 1-liter bottles
Compounds
| Component | Amount per 1 ml |
|---|---|
| Doxycycline (Hyklate) | 100 mg |
| Carriers | q.s. to 1 ml |
Mechanism of the Effect
Doxycycline binds to the 30S subunit of the bacterial ribosome, preventing the attachment of aminoacyl-tRNA to the acceptor site of the ribosome.
This action inhibits bacterial protein synthesis, thereby stopping bacterial growth and reproduction.
Doxycycline has a bacteriostatic effect and is effective against Gram-positive and Gram-negative bacteria, as well as Mycoplasma and Rickettsia species.
Use case
Used for the treatment of Chronic Respiratory Disease (CRD), mycoplasmosis, avian cholera, and colibacillosis caused by doxycycline-sensitive organisms in poultry.
The amount and how to use
Oral administration via drinking water:
10–20 mg of doxycycline per kg of body weight per day for 3 to 5 consecutive days
(equivalent to 0.5–1 ml of the drug per liter of drinking water).
The medicated water should be the only source of drinking water during the treatment period.
Prepare fresh medicated water every 24 hours.
In alkaline water, it is recommended to use water acidifiers before adding this drug to the water.
Caution
Shake the medication bottle well before use.
Keep out of reach of children.
Drug interference
Drug interactions of veterinary doxycycline include:
Reduced absorption when taken with drugs containing calcium, iron, and magnesium.
Decreased effectiveness when combined with bacteriostatic antibiotics.
Increased risk of bleeding with anticoagulant drugs.
Concurrent use with NSAIDs may increase the risk of kidney toxicity.
Maintenance conditions
Veterinary Doxyten should be stored in a dry, cool place, away from direct sunlight and temperatures above 25°C. Protect from freezing. Keep out of reach of children and animals.
