آموکسی وت 80

Amoxicillin Trihydrate 80%

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Available in 1 kg sachets

Each gram of product contains: 800 mg amoxicillin trihydrate (equivalent to 697 mg pure amoxicillin)

Amoxicillin – Pharmacological Overview Amoxicillin is a semi-synthetic, time-dependent, bactericidal antibiotic that acts by inhibiting bacterial cell wall synthesis during replication. It achieves this by binding irreversibly to penicillin-binding proteins (PBPs), leading to cell lysis and bacterial death. It is a broad-spectrum β-lactam antibiotic, effective against both Gram-positive and Gram-negative bacteria, including those with lipopolysaccharide and protein-rich outer membranes. Pharmacokinetics: Well absorbed orally, with good stability in gastric acid Widely distributed in body fluids and tissues Primarily excreted unchanged via the kidneys, ensuring high urinary concentrations

Amoxicillin Trihydrate 80% – Indications in Poultry and Turkeys This product is used for the treatment of gastrointestinal, respiratory, and urinary tract infections in chickens and turkeys, caused by amoxicillin-sensitive bacteria, including: Campylobacter Clostridium Escherichia coli (E. coli) Erysipelothrix Haemophilus Pasteurella Salmonella Staphylococcus Streptococcus Although effective against all the above pathogens, this formulation is particularly indicated for the treatment of necrotic enteritis in poultry—a disease primarily caused by Clostridium perfringens.

Species Dosage (per kg body weight/day) Water-Based Dosage Duration Broilers, pullets, breeders 15 mg amoxicillin trihydrate (≈13.1 mg pure amoxicillin) → ≈18.8 mg product 250 g in 1000–2000 L drinking water 3 days (up to 5 in severe cases) Turkeys 15–20 mg amoxicillin trihydrate (≈13.1–17.4 mg pure amoxicillin) → ≈18.8–25 mg product 250–333 g in 1000–2000 L drinking water 3 days (up to 5 in severe cases) Ducks 20 mg amoxicillin trihydrate (≈17.4 mg pure amoxicillin) → 25 mg product — 3 consecutive days > 💧 Important: Any medicated water remaining after 12 hours must be discarded to ensure potency and prevent microbial resistance.

Storage and Handling Instructions Use the product within 6 months after opening the packaging. Once dissolved in drinking water, the solution must be used within 12 hours. After opening, seal the container tightly to prevent moisture ingress and maintain product quality.

Do not co-administer with bacteriostatic antibiotics such as tetracyclines, macrolides, or sulfonamides, as they may antagonize the bactericidal effect of amoxicillin by interfering with its mechanism of action—inhibition of cell wall synthesis during active bacterial replication. Avoid concurrent use with neomycin, as it can impair the gastrointestinal absorption of amoxicillin, reducing its systemic availability and therapeutic efficacy