Clonil Plus Royan

Claniel Plus Royan

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100, 200, 250, 500, 1000, and 2000 mL bottles

Each liter of the oral solution contains: 25 g Oxfendazole 50 g Closantel (sodium salt)

Oxfendazole is a benzimidazole anthelmintic effective against a wide range of pathogenic internal parasites.
It is believed to disrupt intracellular microtubule transport systems by selectively binding to and damaging tubulin, thereby inhibiting tubulin polymerization and microtubule formation.
At higher concentrations, it also interferes with the metabolic pathways of parasites by inhibiting key enzymes such as malate dehydrogenase and fumarate reductase.

Closantel is a salicylanilide compound used to control and treat immature and mature flukes, nematodes, and larval stages of various arthropods.
It acts by interfering with oxidative phosphorylation in parasite mitochondria, thereby disrupting energy metabolism.
Other mechanisms such as interference with glycolysis and reduction of cellular ATP further enhance its efficacy.

This product is used for the treatment of mixed infections caused by adult and immature gastrointestinal and pulmonary roundworms, tapeworms, flukes, and nasal bot fly larvae in sheep and lambs.
It is also effective against the eggs of roundworms and delays egg-laying in trematodes (flukes).

Administer orally at a dose of 1 mL per 5 kg body weight (equivalent to 5 mg Oxfendazole and 10 mg Closantel per kg body weight) as a single dose.

Avoid skin contact.
Do not eat, drink, or smoke while handling the product.
Wear protective clothing such as impermeable gloves.
In case of accidental ingestion, seek medical help immediately.
May cause temporary blindness, nausea, or vomiting in humans.
Wash hands after use.
Keep out of reach of children.